The Non Invasive Prenatal Test for detecting fetal chromosomal abnormalities during pregnancy
Prenatalsafe® provides detailed information on the baby’s health before birth.
The Non Invasive Prenatal Test for detecting fetal chromosomal abnormalities during pregnancy
Prenatalsafe® provides detailed information on the baby’s health before birth.
Prenatal Screening Tests
Prenatal Screening Tests are analyses performed during pregnancy to assess the health of the fetus.
These tests allow early detection of diseases associated with DNA variants and abnormalities in the number or structure of chromosomes.
Being informed is the first step to obtaining assistance in childbirth or to initiating, when possible, a course of treatment before or immediately after the birth of the child.
Prenatalsafe®, the innovative non-invasive prenatal test to detect chromosomal abnormalities and genetic diseases directly on the fetus, is the result of Eurofins Genoma’s OrizzonteNascita project.
Prenatalsafe® is the most complete non-invasive prenatal screening test that analyzes fetal DNA extracted from a maternal blood sample.
It allows you to identify the presence of abnormalities in chromosomes, both in number (aneuploidies) and in structure. Abnormalities that are the basis of some of the most common genetic diseases.
It offers 9 levels of depth, thanks to which it is possible to obtain an extremely complete informational picture starting from the 10th week of pregnancy.
What are aneuploidies?
Aneuploidies are genetic abnormalities, characterized by a higher or lower number of chromosomes than the standard number, leading to deficits or disabilities.
How is it done?
the Prenatalsafe® test is performed with a simple maternal blood sample.
Prenatalsafe® minimizes the risks of abortiveness related to traditional invasive prenatal diagnostic techniques, such as amniocentesis and chorionic villus sampling.
Simple
A simple mother’s blood sample is required at the 10th week of gestation.
Safe
It is a non-invasive test, reducing the risks of abortion present in traditional invasive prenatal diagnostic techniques, such as amniocentesis and villocentesis.
Fast
Thanks to the high-resolution FAST protocol, test results will be available after just 3 working days.
Complete
It is 99.9% reliable. It can detect anomalies even if there is a low amount of fetal DNA in maternal blood, unlike other tests that require a higher amount of fetal DNA.
Clear Results
Definite outcome: positive or negative test result
Prenatalsafe® is available in 9 versions, each with a different level of depth.
It is available throughout Italy and the analyses are performed at the Eurofins Genoma laboratories in Milan, Rome and Florence.
3
Evaluates the aneuploidies of chromosomes 21 (Down syndrome), 18 (Edwards syndrome), 13 (Patau syndrome), and includes the determination of fetal sex (optional).
5
Evaluates the aneuploidies of chromosomes 21 (Down syndrome), 18 (Edwards syndrome), 13 (Patau syndrome) and sex chromosomes, and includes the determination of fetal sex (optional).
5DiGeorge
Evaluates the aneuploidies of chromosomes 21 (Down syndrome), 18 (Edwards syndrome), 13 (Patau syndrome), sex chromosome aneuploidies and the microdeletion of chromosome 22 (DiGeorge syndrome).
Plus
In addition to what is provided by the Prenatalsafe® 5 test, it also includes the option for further investigation to identify trisomy of chromosomes 9 and 16 and the presence of structural chromosomal alterations, i.e. 6 of the most common microdeletion syndromes.
Karyo
Detects fetal aneuploidies and structural chromosomal alterations in every chromosome (deletions and segmental duplications).
Karyo Plus
Adds the study of 9 of the most common microdeletion syndromes to the capabilities of Prenatalsafe® Karyo.
Complete
It is one of the most technologically advanced non-invasive prenatal tests.
By analyzing the circulating fetal DNA in maternal blood, it is capable of performing the fetal karyotype screening and serious fetal genetic diseases.
Complete Plus
Adds the study of 9 of the most common microdeletion syndromes to the capabilities of Prenatasafe® Complete.
Full risk
Adds the Genescreen® focus test, a carrier screening for both parents that identifies mutations related to recessive hereditary diseases that can potentially be transmitted to the fetus, to the benefits of Prenatasafe® Complete Plus.
A complete and innovative non-invasive prenatal test, suitable for any different need.
Who we recommend Prenatalsafe® to
The Prenatalsafe® examination is the best test in the following cases:
Pregnancies in which prenatal invasive diagnosis is contraindicated (e.g. risk of spontaneous abortion)
First trimester (bi-test) positive
Advanced maternal age (>35 years)
Advanced paternal age (>40 years)
Previous cases of chromosomal anomalies in the family
Parent carrying a balanced translocation
Prenatalsafe® tests can be performed starting from the 10th week of gestation (calculated from LMP) and every future mother can undergo the tests.
Eurofins Genoma offers free consulting to advise on the most appropriate analysis for each couple’s needs.
Prenatalsafe® is useful in the following cases:
Single
pregnancies
Obtained through natural conception or assisted fertility techniques.
Twin
pregnancies
Obtained through natural conception or assisted fertility techniques.
Previous
miscarriages
Pregnancies ended with spontaneous abortion or voluntary interruption.
Get your results in record time:
| Test | Turnaround Time |
|---|---|
| Prenatalsafe® 3 | 3 business days |
| Prenatalsafe® 5 | 3 business days |
| Prenatalsafe® 5DiGeorge | 3 business days |
| Prenatalsafe® Plus | 5 to 7 business days |
| Prenatalsafe® Karyo | 4 to 5 business days |
| Prenatalsafe® Karyo Plus | 5 to 7 business days |
| Prenatalsafe® COMPLETE | 4 to 15 business days |
| Prenatalsafe® COMPLETE Plus | 5 to 15 business days |
| Prenatalsafe® FULL RISK | 5 to 20 business days |
Test |
|---|
Prenatalsafe® 3Turnaround Time: 3 business days |
Prenatalsafe® 5Turnaround Time: 3 business days |
Prenatalsafe® 5DiGeorgeTurnaround Time: 3 business days |
Prenatalsafe® PlusTurnaround Time: 5 to 3 business days |
Prenatalsafe® KaryoTurnaround Time: 4 to 5 business days |
Prenatalsafe® Karyo PlusTurnaround Time: 5 to 7 business days |
Prenatalsafe® COMPLETETurnaround Time: 4 to 15 business days |
Prenatalsafe® COMPLETE PlusTurnaround Time: 5 to 15 business days |
Prenatalsafe® FULL RISKTurnaround Time: 5 to 20 business days |