The test to assess the presence of genetic diseases in the couple before embryo implantation
Embryosafe® prevents the transmission of genetic diseases to the embryo: for a safe and risk-free assisted conception.
The test to assess the presence of genetic diseases in the couple before embryo implantation
Embryosafe® prevents the transmission of genetic diseases to the embryo: for a safe and risk-free assisted conception.
Some anomalies in the DNA sequence can make a person a carrier of a specific genetically transmitted disease.
Healthy carriers of genetic diseases are healthy individuals, without symptoms and unaware of being at risk of transmitting their pathology to their children.
1 OUT OF 4
The child of two healthy carriers is born with a genetic condition.
Before proceeding with the implantation of the embryo, it is important to make sure that one is not a healthy carrier of any genetically transmitted diseases. Being aware of one’s pathologies is the first step for the success of fertilization and for a serene and risk-free pregnancy.
Be aware and trust us: for over 20 years, Eurofins Genoma has been by your side in this journey.
All the answers you need, in a single solution designed for you.
Embryosafe® s a test created by Eurofins Genoma for Preimplantation Genetic Diagnosis (PGD): a set of techniques that allow the detection of genetic diseases in embryos, before they are transferred to the uterus.
PGD can be considered a very early form of prenatal diagnosis.
What is the purpose?
Before starting a clinical pregnancy, all genetic diseases that parents could transmit to children are diagnosed. At this point, only healthy embryos after the pathology analysis are selected and transferred to the uterus.
As a result, thanks to Embryosafe®, couples avoid having to choose to end the pregnancy if a sick fetus is identified and will have a healthy fetus, free from the analyzed diseases.
Embryosafe® is therefore an addition to assisted reproduction technology and requires in vitro fertilization to allow for manipulation of the embryo before its implantation in the uterus.
Why is Embryosafe® more effective than prenatal diagnosis?
Although prenatal diagnosis techniques today are more than adequate to prevent the birth of children with genetic diseases, couples who use them must face a therapeutic interruption of pregnancy if a fetus affected by the specific disease is identified.
Many couples also face repeated pregnancy interruptions before generating a healthy child.
Embryosafe® was introduced as an alternative to prenatal diagnosis, to increase the options available to couples who know they have a genetically transmitted disease.
Embryosafe® minimizes the presence of genetic pathologies.
From the ‘90 to today: PGD as an established solution.
After its first application in 1990, PGD has added to the approaches typically used for the prevention of genetic diseases and has become a consolidated clinical option in reproductive medicine.
PGD has reduced the number of spontaneous abortions by preventing the conception of children with pathologies.
Since then, the number of centers that perform Preimplantation Genetic Diagnosis has increased constantly, along with the number of diseases that can be identified.
Eurofins Genoma performed the first case of PGD in 1998, in a couple at risk of fibrosis
Our lab’s PGD section has intense scientific collaboration with prestigious international institutes and ongoing interaction with the International Scientific Community.
We use the most modern equipment and the most advanced technologies available today, employing sophisticated and innovative methods.
We are the most qualified Italian center in the field of pre-implantation genetic diagnosis and a reference point for several assisted fertilization centers, both national and international.
We also study cases of rare genetic diseases where a genetic diagnosis is usually not available, developing an ad hoc PGD strategy for the specific mutations present in the couple.
How is Embryosafe® performed?
The execution of Embryosafe® involves the following steps:
Induction of ovulation
Retrieval of mature oocytes
In vitro fertilization
through intracytoplasmic injection (ICSI)
Embryo biopsy
Genetic analysis of the blastomere
Implantation of embryos in the uterus